@article {KNZ001334,
	title = {Comparative genome scan detects host-related divergent selection in the grasshopper Hesperotettix viridis},
	journal = {Molecular Ecology},
	volume = {19},
	year = {2010},
	pages = {4012 -4028},
	abstract = {<p>In this study, we used a comparative genome scan to examine patterns of population differentiation with respect to host plant use in Hesperotettix viridis, a Nearctic oligophagous grasshopper locally specialized on various Asteraceae including Solidago, Gutierrezia, and Ericameria. We identified amplified fragment length polymorphism (AFLP) loci with significantly elevated FST (outlier loci) in multiple different-host and same-host comparisons of populations while controlling for geographic distance. By comparing the number and identities of outlier loci in different-host vs. same-host comparisons, we found evidence of host plant-related divergent selection for some population comparisons (Solidago- vs. Gutierrezia-feeders), while other comparisons (Ericameria- vs. Gutierrezia-feeders) failed to demonstrate a strong role for host association in population differentiation. In comparisons of Solidago- vs. Gutierrezia-feeding populations, a relatively high number of outlier loci observed repeatedly in different-host comparisons (35\% of all outliers and 2.7\% of all 625 AFLP loci) indicated a significant role for host-related selection in contributing to overall genomic differentiation in this grasshopper. Mitochondrial DNA sequence data revealed a star-shaped phylogeny with no host- or geography-related structure, low nucleotide diversity, and high haplotype diversity, suggesting a recent population expansion. mtDNA data do not suggest a long period of isolation in separate glacial refugia but are instead more compatible with a single glacial refugium and more recent divergence in host use. Our study adds to research documenting heterogeneity in differentiation across the genome as a consequence of divergent natural selection, a phenomenon that may occur as part of the process of ecological speciation.</p>},
	keywords = {LTER-KNZ},
	doi = {10.1111/j.1365-294X.2010.04792.x},
	url = {https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-294X.2010.04792.x},
	author = {Apple, J.L. and Grace, T. and Anthony Joern and Amand, P. and Wisely, S.M.}
}
